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Combo Point Cycles
"Combo point cycle" refers to the algorithm used by a rogue to determine what finishers to use, and in what order, during sustained combat (e.g. against a raid boss). A combo point cycle revolves around keeping SnD active as close to 100% of the time as possible while also keeping Rupture active as much as possible. Eviscerate should only be used if the target is close to death, if the target is bleed-immune, or if you already have SnD and Rupture up with plenty of time left. See the Mechanics section for more about Eviscerate.
On fist/mace/sword cycles: in general, the cycle of choice is Xs/5r. With T4 2pc, 1s/5r or 2s/5r are the likely choices, with 2s/5r being less likely to let SnD drop. Without T4 2pc, 4s/5r or 5s/5r are the choices, with 5s/5r being less likely to let Slice and Dice drop. Do not try to squeeze in extra finishers like Eviscerate. Should the target be immune to bleed effects, use Xs/5e (with T4 2pc, 2s/5e; without it, 5s/5e).
On Hemo cycles: the best current cycle is Xs/5r, with 2s/5r being sustainable if you have T4 2pc, and 5s/5r otherwise. (HELP! If you can think of any better Hemo cycles, or if these are inaccurate, let me know.)
On combat dagger cycles: with T4 2pc, the cycle of choice is Xs/3r, most commonly 1s/3r, although other variants are possible. Typically increasing the CP used on SnD will not result in a gain of SnD uptime, because generating the additional CP will take as long as the amount of extra SnD duration gained. Without T4 2pc, the cycle of choice is 3s/5s/5r. (HELP! Please verify this section is correct. Thanks.)
On combat Mutilate cycles: Mutilate doesn't use a fixed cycle because its CP generation can vary widely. Rather, a Mutilate build uses a general policy of "3+" or "4+", performing finishers after a certain minimum number of CP (either 3 or 4) have been accumulated. Finishers used are SnD, Rupture, and Eviscerate/Envenom, in order of priority (note: see the Mechanics section regarding Envenom). Be sure to balance finisher usage to get the most value out of Find Weakness procs.
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